Categorie: Algemeen (geen categorie)
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1 december 2004 om 10:10 Reactiejeanne van den heuvel,diabetesverpleegkundige
weet u wat de invloed van ginsengpanang capsule van 40 mgr. is op de bloedglucose, 65 jarige heer goed ingesteld met 2x 250 mgr tolbutamide n.glucose <7 merkt na het innemen van de capsule een gevoel van warmte na 15 min en voelt zich beverig, meet hij, dan heeft hij een glucose >10 en na 2 uur meten weer glucose <7, graag uw reactie, bijvoorbaat dank jeanne van de heuvel diabetees verpleegkundige zorg en welzijngroep zuid-hollandse eilanden.
1 december 2004 om 10:54 Reactiediabetes2.nlGeachte collega,
Voor dit specifieke preparaat weet ik het niet. Vorig jaar is een systematische review verschenen over de invloed van kruiden en supplementen op de glycemische regulatie. Hieronder staat de tekst betreffende Ginseng. De laatste zin is: "The available evidence for American ginseng in diabetes suggests a possible hypoglycemic effect; however, the trials are small and longer-term studies are needed."
Dus de eventuele effecten staan nog niet keihard vast!
Met vriendelijke groet,
N. Kleefstra
Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 2003;26:1277-94
Ginseng species
Several different plant species are often referred to as ginseng. These include Chinese or Korean ginseng (Panax ginseng), Siberian ginseng (Eleutherococcus senticosus), American ginseng (P. quiquefolius), and Japanese ginseng (P. japonicus). Panax species (from the root panacea) are often touted for their "cure-all" adaptogenic properties, immune-stimulant effects, and their ability to increase stamina, concentration, longevity, and overall well-being. Preparations use the herb’s root; some sources report greater efficacy with roots that are greater than 3 years old. Principal components are believed to be the triterpenoid saponin glycosides (ginsenosides or panaxosides). Hypoglycemic effects have been shown in streptozotocin rat models. Reported mechanisms of action include decreased rate of carbohydrate absorption into the portal hepatic circulation, increased glucose transport and uptake mediated by nitric oxide, increased glycogen storage, and modulation of insulin secretion.Most clinical trials we found utilized American ginseng, with many examining the herb’s short-term effects on patients with type 2 diabetes after a standard oral GTT. Two longer-term trials administered American ginseng for 8 weeks (n = 36 and n = 24); both reported decreases in fasting blood glucose and HbA1c. Only one case of insomnia was reported in these trials. Three other short-term metabolic trials in healthy volunteers also found decreases in postprandial glucose. All but one of the clinical trials we examined were from the same investigator group. The available evidence for American ginseng in diabetes suggests a possible hypoglycemic effect; however, the trials are small and longer-term studies are needed. (Level I, A)
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